Mesenchymal stromal cell-derived membrane particles suppress kidney fibrosis
Our results demonstrate that MP have anti-fibrotic properties in mouse kidney IRI and human kidney organoid models. These results indicate that MP have potential for the development of kidney fibrosis-inhibiting therapy.
Authors
- Shengbing Li (ORCID: https://orcid.org/0009-0001-2429-714X)
- Carla C. Baan (ORCID: https://orcid.org/0000-0003-2274-2788)
- Ana Merino (ORCID: https://orcid.org/0000-0002-8322-4047)
- Marlies E. J. Reinders (ORCID: https://orcid.org/0000-0001-9543-567X)
- Thierry van den Bosch (ORCID: https://orcid.org/0000-0002-7223-4565)
- Martin J. Hoogduijn (ORCID: https://orcid.org/0000-0002-0217-8254)
- Sander S. Korevaar
Institutions
- Erasmus MC (NL)
- Thermo Fisher Scientific (Netherlands) (NL)
- Erasmus MC Cancer Institute (NL)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-07-26
- DOI
- https://doi.org/10.1186/s13287-025-04522-z
- Citations
- 1
- Primary Topic
- Renal and related cancers
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Health~Holland