Visible‐Light‐Induced α‐C(<i>sp</i><sup>3</sup>)‐H Alkylation of 1,3,4‐Oxadiazoles via 1,2‐Hydrogen Atom Transfer
A novel example of visible‐light‐induced α‐C( sp 3 )‐H alkylation of 1,3,4‐oxadiazoles via 1,2‐hydrogen atom transfer is reported. A broad range of 1,3,4‐oxadiazoles and N ‐aroyloxyamides are successfully transformed into the corresponding products in moderate to excellent yields. The protocol features mild reaction conditions, broad substrate scope, excellent functional group compatibility, and simple operation procedure.
Authors
- Hui Sun (ORCID: https://orcid.org/0000-0003-4677-7299)
- Guanghui Lv (ORCID: https://orcid.org/0000-0003-4846-9564)
- Yong Wu (ORCID: https://orcid.org/0000-0003-0719-4963)
- Cuimei Zhang (ORCID: https://orcid.org/0000-0002-3682-1834)
- Mi Wang (ORCID: https://orcid.org/0000-0003-2799-5987)
- Jian Chen (ORCID: https://orcid.org/0000-0001-5128-8567)
- Dongqin He
- Yafei Zhu (ORCID: https://orcid.org/0009-0000-1002-0708)
Institutions
- Hubei University of Medicine (CN)
- Sichuan University (CN)
Publication Details
- Journal
- European Journal of Organic Chemistry
- Published
- 2025-07-26
- DOI
- https://doi.org/10.1002/ejoc.202500605
- Citations
- 1
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.94