Visible-Light-Mediated Cascade Arylcarboxylation/Cyclization of <i>N</i>-Aryl/Benzoyl Acrylamide with CO₂

A visible-light-mediated radical cascade arylcarboxylation/cyclization of <i>N</i>-alkyl-<i>N</i>-methacryloylbenzamides and <i>N</i>-alkyl-<i>N</i>-arylmethacrylamides with carbon dioxide (CO₂) was established. The reactions employed economical CO₂ as the carboxyl source, cesium carbonate as the base, triphenylsilane as the additive, and <i>fac</i>-Ir(ppy)₃ as the photocatalyst. Novel 1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-4-ylacetic acid derivatives and oxindole-3-acetic acid derivatives were obtained in moderate to good yields. This methodology shows a wide substrate scope, simple operation, excellent functional group compatibility, mild conditions, gram scale synthesis, and straightforward product derivatization. Detailed mechanistic insights reveal that CO₂^•- generated <i>in situ</i> was invovled as key a key active intermediate under conditions free of external hydrogen atom transfer (HAT) and reducing agents.