The synergic impact of decellularized testis scaffold and extracellular vesicles derived from human semen on spermatogonial stem cell survival and differentiation
The findings underscore the potential of integrating SEV-laden decellularized scaffolds to partially promote SSC differentiation for fertility restoration in spermatogenic failure.
Authors
- Ali Golestan
- Tahereh Talaei‐Khozani (ORCID: https://orcid.org/0000-0002-8425-8871)
- Mehri Shadi
- Sanaz Alaee (ORCID: https://orcid.org/0000-0003-4490-8830)
- Pooneh Mokarram (ORCID: https://orcid.org/0000-0002-9717-0473)
- Mahintaj Dara (ORCID: https://orcid.org/0000-0003-0087-3162)
- Noshafarin Chenari
- Farideh Afshari
- Amin Ramezani (ORCID: https://orcid.org/0000-0001-5655-8722)
Institutions
- Shiraz University of Medical Sciences (IR)
- Stem Cell Technology Research Center (IR)
- West Kazakhstan Marat Ospanov State Medical University (KZ)
- Birjand University of Medical Sciences (IR)
Publication Details
- Journal
- BioMedical Engineering OnLine
- Published
- 2025-07-26
- DOI
- https://doi.org/10.1186/s12938-025-01424-2
- Citations
- 3
- Primary Topic
- Tissue Engineering and Regenerative Medicine
- Type
- article
- Field-Weighted Citation Impact
- 6.02
Funders
- Shiraz University of Medical Sciences
- Shiraz University