TiME for a change: The tumor microenvironment as the missing piece in cancer therapeutics
Cancer treatments often fall short of durable cures, yet most therapeutic strategies neglect the tumor stroma. A concerted effort is needed to understand, model, target and reprogram the tumor 'soil', recognizing its profound influence on cancer from tumorigenesis to therapy resistance.
Authors
- Hanyun Zhang (ORCID: https://orcid.org/0000-0002-4140-7881)
- Alexander Swarbrick (ORCID: https://orcid.org/0000-0002-3051-5676)
- Jeremy Mo
Institutions
- The University of Sydney (AU)
- Garvan Institute of Medical Research (AU)
- UNSW Sydney (AU)
- St Vincent's Clinic (AU)
Publication Details
- Journal
- PLoS Biology
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1371/journal.pbio.3003276
- Citations
- 5
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 5.23
Funders
- Breast Cancer Research Foundation
- Petre Foundation
- National Health and Medical Research Council