An <i>S</i><sub>4</sub>-Symmetrical Multi-Macrocyclic Nanohoop Derived from a 1,3-Alternate Calix[4]arene Core
Combining conjugated paraphenylene macrocycles with other functional macrocyclic units presents a promising approach for expanding the structural and functional diversity of multi-macrocyclic molecules. Herein, we report a macrocyclic nanohoop with <i>S</i><sub>4</sub> symmetry, composed of a 1,3-alternate calix[4]arene core and two oligo(paraphenylene) segments. Structurally, this macrocycle features interconnected cavities, and functionally, it inherits the fluorescence of the paraphenylene frameworks and the ion-binding capability of calixarenes. Remarkably, this macrocycle exhibits selective fluorescence responses toward potassium and uranyl ions. Theoretical calculations further reveal the nature of the noncovalent interactions for metal ion recognition.
Authors
- Huan Cong (ORCID: https://orcid.org/0000-0003-1687-2404)
- Yu Qiu (ORCID: https://orcid.org/0000-0003-1069-4520)
- Liang‐Liang Mao
- Jia‐Nan Gao
- Heng Wang (ORCID: https://orcid.org/0009-0009-4627-7826)
- Kunshan Xue
Institutions
- Chinese Academy of Sciences (CN)
- Shanghai Institute of Organic Chemistry (CN)
- Technical Institute of Physics and Chemistry (CN)
- University of Chinese Academy of Sciences (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1021/acs.orglett.5c02677
- Citations
- 4
- Primary Topic
- Molecular Sensors and Ion Detection
- Type
- article
- Field-Weighted Citation Impact
- 3.03
Funders
- National Natural Science Foundation of China
- Technical Institute of Physics and Chemistry of the Chinese Academy of Sciences
- National Key Research and Development Program of China