Soluble Receptor for Advanced Glycation End Products and Incident Hypertension in REGARDS
Higher baseline sRAGE levels were not associated with lower risk of incident hypertension after adjusting for known confounders. Low sRAGE might represent adverse inflammation that drives hypertension rather than being a primary driver of hypertension development itself.
Authors
- Nels C. Olson (ORCID: https://orcid.org/0000-0003-1192-9969)
- Timothy B. Plante (ORCID: https://orcid.org/0000-0001-9992-9597)
- D. Leann Long (ORCID: https://orcid.org/0000-0001-8614-7190)
- Suzanne E. Judd (ORCID: https://orcid.org/0000-0001-7594-6587)
- Virginia J. Howard (ORCID: https://orcid.org/0000-0003-4912-9975)
- Sarah Krumholz
- Mary Cushman
Institutions
- University of Vermont (US)
- Alabama Department of Public Health (US)
- University of Alabama at Birmingham (US)
- Wake Forest University (US)
Publication Details
- Journal
- American Journal of Hypertension
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1093/ajh/hpaf109
- Citations
- 2
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- U.S. Department of Health and Human Services
- National Institutes of Health
- National Institute on Aging
- National Institute of Neurological Disorders and Stroke