Lebrikizumab improves head/neck/face dermatitis and erythema and does not increase treatment-emergent adverse events of head/neck/face erythema in patients with moderate-to-severe atopic dermatitis
LEBRI improved EASI HN subscore and HN EASI clinical signs of erythema and facial dermatitis at Week 16. During the PBO-controlled period, an increased reporting of HN and facial erythema as TEAE was not observed in the LEBRI group and HN and facial TEAEs reporting did not increase with longer exposure.
Authors
- Jenny E. Murase (ORCID: https://orcid.org/0000-0002-7529-9778)
- Hany Elmaraghy (ORCID: https://orcid.org/0000-0003-3552-9345)
- Ignasi Pau‐Charles (ORCID: https://orcid.org/0000-0002-7960-7045)
- Maria Lucia Buziqui Piruzeli
- Christine Bangert (ORCID: https://orcid.org/0000-0003-3392-6590)
- Raj Chovatiya (ORCID: https://orcid.org/0000-0001-6510-399X)
- Mette Deleuran (ORCID: https://orcid.org/0000-0003-0593-9925)
- D. Staumont‐Sallé (ORCID: https://orcid.org/0000-0002-4780-4212)
- Hwanhee Hong (ORCID: https://orcid.org/0000-0002-3736-6327)
- Amber Reck Atwater (ORCID: https://orcid.org/0000-0001-7434-0014)
- Lindsay C. Strowd (ORCID: https://orcid.org/0000-0003-3803-5527)
- Kilian Eyerich (ORCID: https://orcid.org/0000-0003-0094-2674)
- Jinglin Zhong (ORCID: https://orcid.org/0000-0002-6249-112X)
- Fan Emily Yang
- María José Rueda
Institutions
- University of British Columbia (CA)
- Eli Lilly (United States) (US)
- University of California, San Francisco (US)
- Rosalind Franklin University of Medicine and Science (US)
- Université de Lille (FR)
- University Medical Center Freiburg (DE)
- Aarhus University Hospital (DK)
- IQVIA (United Kingdom) (GB)
- SKiN Health (CA)
- University of Chicago Medical Center (US)
- IQVIA (United States) (US)
- Almirall (Spain) (ES)
- Palo Alto Institute (US)
- Medical Research Foundation (GB)
- Wake Forest University (US)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Journal of Dermatological Treatment
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1080/09546634.2025.2492188
- Citations
- 2
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- Dermira