Sophoridine inhibits proliferation and migration by targeting PIM1 in breast cancer
Taken together, sophoridine relies on targeting PIM1 to inhibit cell proliferation and migration in breast cancer, which might be related to the activation of ASK1/MAPK axis, suggesting the therapeutic potential of sophoridine for breast cancer.
Authors
- Da Huang (ORCID: https://orcid.org/0000-0002-6203-9459)
- Yuqin Zhang (ORCID: https://orcid.org/0000-0002-1449-6209)
- Yuting Xia (ORCID: https://orcid.org/0000-0001-5684-3195)
- Liangliang Min
- Zhi‐Hua Li (ORCID: https://orcid.org/0000-0002-6484-657X)
- Lu Chen (ORCID: https://orcid.org/0000-0002-8097-2699)
- Yulu Zhang (ORCID: https://orcid.org/0000-0002-5551-3597)
- Arthur Xintian You
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Jiangxi Provincial People's Hospital (CN)
- Third Hospital of Nanchang (CN)
- Second Hospital of Nanchang (CN)
- Community Health Center (US)
Publication Details
- Journal
- Pharmaceutical Biology
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1080/13880209.2025.2537123
- Primary Topic
- Cancer Mechanisms and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00