Shield ulcer in keratoconus in the absence of atopic or vernal kerato-conjunctivitis

Corneal shield ulcer is a severe complication of atopic keratoconjunctivitis (AKC) and vernal keratoconjunctivitis (VKC). This condition is caused by the mechanical irritation of the corneal epithelium due to giant papillae and toxic epitheliopathy resulting from inflammatory mediators. To date, there have been no reported cases of corneal shield ulcers in the literature without AKC or VKC. However, the authors have reported a unique case of shield ulcer in a patient with keratoconus but no history of AKC or VKC. The cause is hypothesised to be due to mechanical friction between the corneal steep apex and palpebral conjunctiva. Additionally, a new technique, the use of a dry amniotic membrane, is described to manage the persistent epithelial defect in shield ulcers.

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Publication Details

Journal
PubMed
Published
2025-06-12
DOI
https://doi.org/10.3205/oc000253
Primary Topic
Corneal Surgery and Treatments
Type
article
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article

Shield ulcer in keratoconus in the absence of atopic or vernal kerato-conjunctivitis

Magdalena Niestrata-Ortiz, Zahra Ashena, Shuchi Kohli, Mohammad Saleki
PubMed
Corneal Surgery and Treatments
article

Shield ulcer in keratoconus in the absence of atopic or vernal kerato-conjunctivitis

Magdalena Niestrata-Ortiz, Zahra Ashena, Shuchi Kohli, Mohammad Saleki
article en

Abstract

Corneal shield ulcer is a severe complication of atopic keratoconjunctivitis (AKC) and vernal keratoconjunctivitis (VKC). This condition is caused by the mechanical irritation of the corneal epithelium due to giant papillae and toxic epitheliopathy resulting from inflammatory mediators. To date, there have been no reported cases of corneal shield ulcers in the literature without AKC or VKC. However, the authors have reported a unique case of shield ulcer in a patient with keratoconus but no history of AKC or VKC. The cause is hypothesised to be due to mechanical friction between the corneal steep apex and palpebral conjunctiva. Additionally, a new technique, the use of a dry amniotic membrane, is described to manage the persistent epithelial defect in shield ulcers.

PubMedVol. 15
Queen's Hospital (GB)
Openalex Percentile: Top 73%
Corneal Surgery and Treatments
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