Exploring the role of curcumin, nanocurcumin, and a PPAR agonist in preventing paraquat-induced systemic inflammation and oxidative stress in rats.
The amelioration of systemic inflammation and oxidative stress caused by inhaled PQ by Cu, NC, and Pio were shown. Furthermore, the findings indicated a synergistic effect between Pio with Cu and NC, suggesting the involvement of PPARγ-mediated mechanisms in the effects of curcumin.
Authors
- Mohammad Hossein Boskabady (ORCID: https://orcid.org/0000-0001-5736-9755)
- Mahboobeh Ghasemzadeh Rahbardar (ORCID: https://orcid.org/0000-0002-5491-572X)
- Mohammad Ehsan Taghavizadeh Yazdi (ORCID: https://orcid.org/0000-0003-0086-8005)
- Hasan Al Amin
- Sima Beigoli
Institutions
- Mashhad University of Medical Sciences (IR)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.22038/ijbms.2025.82057.17753
- Citations
- 6
- Primary Topic
- Paraquat toxicity studies and treatments
- Type
- article
- Field-Weighted Citation Impact
- 12.04
Funders
- National Science Foundation
- Ferdowsi University of Mashhad
- Iran National Science Foundation
- Mashhad University of Medical Sciences