Fyn kinase mediates the development of rats with chronic obstructive pulmonary disease by modulating the activation of p38 MAPK and NF-κB.
Collectively, these data show that Fyn promotes COPD development by modulating the p38 MAPK and NF-κB signaling pathways. Fyn might be a promising therapeutic target for COPD.
Authors
- Nan Shen (ORCID: https://orcid.org/0000-0002-5875-4417)
- Qiangqiang Chu
- Yong‐Xiang Wu (ORCID: https://orcid.org/0000-0003-1054-2105)
- Jun Ding (ORCID: https://orcid.org/0000-0003-3752-1750)
- Peng Song (ORCID: https://orcid.org/0000-0002-1748-5580)
- Feng Chu
- Yanbei Zhang (ORCID: https://orcid.org/0000-0002-1035-3681)
Institutions
- Bengbu Medical College (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.22038/ijbms.2025.82400.17818
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Anhui Medical University