Myocardial kinetics of [11C]β-hydroxybutyrate in healthy pigs: Comparison of positron emission tomography imaging vs. arteriovenous balance methods

[<sup>11</sup>C]OHB PET imaging is a non-invasive tool for assessing myocardial ketone metabolism, providing valuable insights into ketone uptake and oxidation in vivo, with potential for extrapolation to human data.

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Publication Details

Journal
Nuclear Medicine and Biology
Published
2025-07-19
DOI
https://doi.org/10.1016/j.nucmedbio.2025.109053
Primary Topic
Computational Drug Discovery Methods
Type
article
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article

Myocardial kinetics of [11C]β-hydroxybutyrate in healthy pigs: Comparison of positron emission tomography imaging vs. arteriovenous balance methods

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Myocardial kinetics of [11C]β-hydroxybutyrate in healthy pigs: Comparison of positron emission tomography imaging vs. arteriovenous balance methods

Aage Kristian Olsen Alstrup, Lars Poulsen Tolbod, Nigopan Gopalasingam, Erik Nguyen Nielsen, Lars Christian Gormsen, Ole Lajord Munk, Mette Louise Gram Kjærulff, Mie Ringgaard Dollerup
article en

Abstract

[<sup>11</sup>C]OHB PET imaging is a non-invasive tool for assessing myocardial ketone metabolism, providing valuable insights into ketone uptake and oxidation in vivo, with potential for extrapolation to human data.

Nuclear Medicine and BiologyVol. 148-149
Aarhus University Hospital (DK)
Openalex Percentile: Top 80%
Computational Drug Discovery Methods
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