Clinicopathological significance of histological diversity in gastric adenocarcinoma with primitive enterocyte phenotype: A methylation-driven aggressive entity
The diversity and aggressiveness of GAPEP are driven by deregulated methylation, necessitating the integration of morphological and immunohistochemical diagnosis. Targeting methylation can provide new therapeutic opportunities for treating this aggressive cancer.
Authors
- Shanshan Lv
- Hou-Qiang Li
- Xunbin Yu
- Lanqing Zheng
- Xin Yan (ORCID: https://orcid.org/0000-0002-9135-7915)
- Xiaohong Chen (ORCID: https://orcid.org/0000-0002-9797-8384)
- Wentao Huang (ORCID: https://orcid.org/0000-0003-0843-2417)
- Lin Lan (ORCID: https://orcid.org/0000-0001-9883-0026)
- Xia Zhang (ORCID: https://orcid.org/0009-0007-0317-8671)
Institutions
- Fujian Medical University (CN)
- Fujian Provincial Hospital (CN)
Publication Details
- Journal
- World Journal of Gastroenterology
- Published
- 2025-07-24
- DOI
- https://doi.org/10.3748/wjg.v31.i28.108990
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00