Optimization of Natural Killer Cell Expansion with K562-mbIL-18/-21 Feeder Cells and Assurance of Feeder Cell-free Products
Our optimized NK cell expansion protocol using irradiated GE-K562 feeder cells and clinical-grade media offers a safe and scalable approach to generating large numbers of NK cells, supporting its potential use in clinical immunotherapy applications.
Authors
- Mijeong Lee (ORCID: https://orcid.org/0000-0003-2477-5647)
- Young-Sang Jo
- Jinho Kim
- J. H. Park (ORCID: https://orcid.org/0000-0002-2662-7122)
- SoonHo Kweon
- Duck Cho (ORCID: https://orcid.org/0000-0001-6861-3282)
- Hantae Jo (ORCID: https://orcid.org/0000-0002-2061-2755)
- Hyun‐Young Kim (ORCID: https://orcid.org/0000-0003-0553-7096)
- Seung Kwon Koh (ORCID: https://orcid.org/0000-0002-7493-8363)
Institutions
- Kangwon National University (KR)
- Cornell University (US)
- Samsung (South Korea) (KR)
- Samsung Medical Center (KR)
- Weill Cornell Medicine (US)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Annals of Laboratory Medicine
- Published
- 2025-07-24
- DOI
- https://doi.org/10.3343/alm.2025.0168
- Citations
- 1
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.80