Retraction Notice to “Phytosomal Curcumin Elicits Anti-tumor Properties ThroughSuppression of Angiogenesis, Cell Proliferation and Induction of Oxidative Stress inColorectal Cancer”

This article titled "Phytosomal Curcumin Elicits Anti-tumor Properties Through Suppression of Angiogenesis, Cell Proliferation and Induction of Oxidative Stress in Colorectal Cancer", published in Volume 24, Issue 39, 2018 of Current Pharmaceutical Design (10.2174/1381612825666190110145151) has been retracted by the publisher following a thorough investigation that revealed potential data manipulation in the manuscript. As a result, the integrity and validity of the data presented could not be confirmed. This article has been retracted at the request of the Editor-in-Chief and the Publisher due to serious ethical and methodological concerns. Post-publication comments highlighted that Figures 2B and 2C depict tumor sizes of 9-10 grams (8,000-9,000 mm3) in 20-gram mice, which violate accepted animal welfare standards. Additionally, concerns were raised regarding Figure 1C, where the flow cytometry data appears inconsistent with standard analysis protocols. Specifically, axis values fall below expected thresholds and suggest incorrect or incomplete data processing. The authors did not provide adequate clarification, raw data, or analysis protocols to resolve these issues. In light of these unresolved concerns, the scientific integrity of the article is compromised, and the article is therefore retracted. Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused. The Bentham Editorial Policy on Retraction can be found at https://benthamscience.com/editorial-policies-main.php. BENTHAM SCIENCE DISCLAIMER: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure, or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication, the authors agree that the publishers have the legal right to take appropriate action against the authors if plagiarism or fabricated information is discovered. By submitting a manuscript, the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.

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Publication Details

Journal
Current Pharmaceutical Design
Published
2025-07-24
DOI
https://doi.org/10.2174/1381612831999250617093855
Primary Topic
Curcumin's Biomedical Applications
Type
article
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article

Retraction Notice to “Phytosomal Curcumin Elicits Anti-tumor Properties ThroughSuppression of Angiogenesis, Cell Proliferation and Induction of Oxidative Stress inColorectal Cancer”

Farzad Rahmani, Seyed Hamid Aghaee‐Bakhtiari, Reyhaneh Moradi‐Marjaneh, Seyed Mahdi Hassanian et al.
1 links
Current Pharmaceutical Design
Curcumin's Biomedical Applications
article

Retraction Notice to “Phytosomal Curcumin Elicits Anti-tumor Properties ThroughSuppression of Angiogenesis, Cell Proliferation and Induction of Oxidative Stress inColorectal Cancer”

Farzad Rahmani, Seyed Hamid Aghaee‐Bakhtiari, Reyhaneh Moradi‐Marjaneh, Seyed Mahdi Hassanian, Majid Khazaei, Amir Avan
article en

Abstract

This article titled "Phytosomal Curcumin Elicits Anti-tumor Properties Through Suppression of Angiogenesis, Cell Proliferation and Induction of Oxidative Stress in Colorectal Cancer", published in Volume 24, Issue 39, 2018 of Current Pharmaceutical Design (10.2174/1381612825666190110145151) has been retracted by the publisher following a thorough investigation that revealed potential data manipulation in the manuscript. As a result, the integrity and validity of the data presented could not be confirmed. This article has been retracted at the request of the Editor-in-Chief and the Publisher due to serious ethical and methodological concerns. Post-publication comments highlighted that Figures 2B and 2C depict tumor sizes of 9-10 grams (8,000-9,000 mm3) in 20-gram mice, which violate accepted animal welfare standards. Additionally, concerns were raised regarding Figure 1C, where the flow cytometry data appears inconsistent with standard analysis protocols. Specifically, axis values fall below expected thresholds and suggest incorrect or incomplete data processing. The authors did not provide adequate clarification, raw data, or analysis protocols to resolve these issues. In light of these unresolved concerns, the scientific integrity of the article is compromised, and the article is therefore retracted. Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused. The Bentham Editorial Policy on Retraction can be found at https://benthamscience.com/editorial-policies-main.php. BENTHAM SCIENCE DISCLAIMER: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure, or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication, the authors agree that the publishers have the legal right to take appropriate action against the authors if plagiarism or fabricated information is discovered. By submitting a manuscript, the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.

Current Pharmaceutical DesignVol. 31(34)
Mashhad University of Medical Sciences (IR)
Openalex Percentile: Top 86%
Curcumin's Biomedical Applications
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