Optimal Utilization of Donors Aged ≥65 Y in Lung Transplantation to Increase Donor Availability While Maintaining Comparable Posttransplant Outcomes

Among lung recipients aged 40-64 y, donor age ≥65 y double transplants yield survival at least matching that of donor age <65 y single transplants. Among recipients aged ≥65 y, donor age ≥65 y double or single transplants yield survival comparable to that of donor age <65 single transplants. Compared with donor age <65 y double transplants, donor age ≥65 y double transplants had only ≤10 mo shorter adjusted median survival, within recipients aged ≥40 y. Judiciously increasing utilization of donors aged ≥65 y within recipients aged ≥40 y can reduce deaths among patients needing a lung transplant by decreasing donor scarcity, while maintaining favorable posttransplant survival.

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Publication Details

Journal
Transplantation Direct
Published
2025-07-24
DOI
https://doi.org/10.1097/txd.0000000000001838
Primary Topic
Transplantation: Methods and Outcomes
Type
article
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article

Optimal Utilization of Donors Aged ≥65 Y in Lung Transplantation to Increase Donor Availability While Maintaining Comparable Posttransplant Outcomes

Manish Mohanka, Craig Fryman, Maksim Korotun, Si M. Pham et al.
Transplantation Direct
Transplantation: Methods and Outcomes
article

Optimal Utilization of Donors Aged ≥65 Y in Lung Transplantation to Increase Donor Availability While Maintaining Comparable Posttransplant Outcomes

Manish Mohanka, Craig Fryman, Maksim Korotun, Si M. Pham, Aldo Iacono, Marniker Wijesinha, Michael L. Terrin
article en

Abstract

Among lung recipients aged 40-64 y, donor age ≥65 y double transplants yield survival at least matching that of donor age <65 y single transplants. Among recipients aged ≥65 y, donor age ≥65 y double or single transplants yield survival comparable to that of donor age <65 single transplants. Compared with donor age <65 y double transplants, donor age ≥65 y double transplants had only ≤10 mo shorter adjusted median survival, within recipients aged ≥40 y. Judiciously increasing utilization of donors aged ≥65 y within recipients aged ≥40 y can reduce deaths among patients needing a lung transplant by decreasing donor scarcity, while maintaining favorable posttransplant survival.

Transplantation DirectVol. 11(8)
University of Maryland, Baltimore (US)
Good health and well-being
Openalex Percentile: Top 69%
Transplantation: Methods and Outcomes
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