Optimal Utilization of Donors Aged ≥65 Y in Lung Transplantation to Increase Donor Availability While Maintaining Comparable Posttransplant Outcomes
Among lung recipients aged 40-64 y, donor age ≥65 y double transplants yield survival at least matching that of donor age <65 y single transplants. Among recipients aged ≥65 y, donor age ≥65 y double or single transplants yield survival comparable to that of donor age <65 single transplants. Compared with donor age <65 y double transplants, donor age ≥65 y double transplants had only ≤10 mo shorter adjusted median survival, within recipients aged ≥40 y. Judiciously increasing utilization of donors aged ≥65 y within recipients aged ≥40 y can reduce deaths among patients needing a lung transplant by decreasing donor scarcity, while maintaining favorable posttransplant survival.
Authors
- Manish Mohanka
- Craig Fryman (ORCID: https://orcid.org/0000-0002-9220-2894)
- Maksim Korotun (ORCID: https://orcid.org/0000-0002-1362-2031)
- Si M. Pham (ORCID: https://orcid.org/0000-0001-7396-8344)
- Aldo Iacono (ORCID: https://orcid.org/0000-0001-8967-6290)
- Marniker Wijesinha (ORCID: https://orcid.org/0000-0002-6609-8456)
- Michael L. Terrin (ORCID: https://orcid.org/0000-0002-6342-2900)
Institutions
- University of Maryland, Baltimore (US)
Publication Details
- Journal
- Transplantation Direct
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1097/txd.0000000000001838
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00