Comparison of [18F]AlF-NOTA-FAPI-04 PET/CT and [18F]FDG PET/CT for diagnosing lymph node metastasis in malignant tumors
[<sup>18</sup>F]AlF-NOTA-FAPI-04 PET/CT demonstrated superior diagnostic performance, semi-quantitative capability, and N staging accuracy compared to [<sup>18</sup>F]FDG PET/CT, particularly for small metastatic lymph nodes (SAD < 10 mm), offering enhanced guidance for tumor staging.
Authors
- Chengzhi Jiang (ORCID: https://orcid.org/0000-0002-9196-9858)
- Kai Zheng (ORCID: https://orcid.org/0000-0002-3488-4946)
- Xiang Peng (ORCID: https://orcid.org/0000-0002-3237-7916)
- Jian Yang (ORCID: https://orcid.org/0000-0001-8170-0727)
- Yanyin Zhang (ORCID: https://orcid.org/0009-0008-5804-4344)
- Wanjing Zhou
- Jiashun Dai
- Hui Ye
Institutions
- Central South University (CN)
- Hunan Cancer Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-07-24
- DOI
- https://doi.org/10.3389/fonc.2025.1605568
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hunan Province