B10 cell-induced PD-L1/PD-1-linked macrophage polarization in periodontitis
B10 cells can regulate macrophage polarization <i>via</i> the PD-L1/PD-1 signalling pathway, thereby suppressing the inflammatory response and reducing alveolar bone resorption during periodontitis. This novel concept can guide future treatment strategies for periodontitis.
Authors
- Yahong Chen (ORCID: https://orcid.org/0000-0003-3258-8032)
- Linxi Zhou (ORCID: https://orcid.org/0000-0003-3935-0633)
- Bing Fang (ORCID: https://orcid.org/0000-0003-2310-8359)
- Lunguo Xia (ORCID: https://orcid.org/0000-0001-6154-9652)
- Xiaozhe Han (ORCID: https://orcid.org/0000-0001-8357-1471)
- Mingyue Fan (ORCID: https://orcid.org/0000-0002-8365-7571)
Institutions
- Nova Southeastern University (US)
- Shanghai Stomatological Hospital (CN)
- Shanghai Ninth People's Hospital (CN)
- Shanghai Xuhui Central Hospital (CN)
- Institute of Immunology (HR)
Publication Details
- Journal
- Journal of Translational Internal Medicine
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1515/jtim-2025-0038
- Citations
- 1
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.80