The route to financial sustainability of a large Public Private Partnership—the example of the clinical trial network conect4children (c4c)

c4c adopted a combined approach, translating research findings into market-tested services through the parallel set-up of a standalone entity, c4c-Stichting (c4c-s). This strategy offers valuable insights into planning financial sustainability for similar large-scale initiatives and, more broadly, provides a significant contribution to the discourse on financial sustainability. These insights are highly relevant to Regulatory Science, as the sustainability of such infrastructures is critical to the success of regulatory science strategy and long-term public health outcomes.