Gut microbiota regulates innate anxiety through neural activity of medial prefrontal cortex in male mice
Our findings establish that gut microbiota modulates innate anxiety through mPFC neural activity, providing novel insights into microbiome-based interventions for anxiety.
Authors
- You‐Lu Wen
- Xiong Cao (ORCID: https://orcid.org/0000-0002-1889-4255)
- Wan-Qian Ye
- Xiao‐Yuan Lian
- Jing Ren (ORCID: https://orcid.org/0000-0002-8223-8762)
- Chenglin Lu (ORCID: https://orcid.org/0009-0005-1837-5358)
Institutions
- Guangdong 999 Brain Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-07-24
- DOI
- https://doi.org/10.3389/fnins.2025.1599818
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation