Comprehensive and advanced T cell cluster analysis for discriminating seropositive and seronegative rheumatoid arthritis
This study advances our understanding of immunological distinctions between SP-RA and SN-RA, identifying key T cell phenotypes as potential targets for SP-RA disease progression. These findings provide a basis for studies on targeted therapeutic strategies tailored to modulate the markers and improve treatment for SP-RA.
Authors
- Tomoyo Maeda
- Taio Naniwa (ORCID: https://orcid.org/0000-0002-0489-2611)
- Akio Niimi (ORCID: https://orcid.org/0000-0003-4947-4760)
- Hiroya Hashimoto (ORCID: https://orcid.org/0000-0003-1865-4953)
- Shin‐ya Tamechika (ORCID: https://orcid.org/0000-0002-5732-1257)
- Shinji Maeda (ORCID: https://orcid.org/0000-0002-5455-8670)
Institutions
- Nagoya City University (JP)
- Nagoya Medical Center (JP)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-07-24
- DOI
- https://doi.org/10.3389/fimmu.2025.1491041
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science