Lactobacillus rhamnosus GG attenuates MASLD/MASH progression by modulating gut microbiota and metabolic pathways
Although LGG shows promise in the treatment of MASLD and MASH, its mechanisms of action and long-term effects require further investigation. Future research should focus on optimizing the types, dosages, and treatment regimens of probiotics, as well as monitoring their long-term impact on gut microbiota balance, to ensure their safety and efficacy in clinical applications.
Authors
- Junhu Fu
- Liang Si
- Siyu Li (ORCID: https://orcid.org/0000-0001-8468-5366)
- Nan Chen (ORCID: https://orcid.org/0000-0002-3429-1542)
- Zhihong Wang
- Shilong Wang (ORCID: https://orcid.org/0000-0001-6086-0481)
- Di Zhu (ORCID: https://orcid.org/0009-0003-6427-8052)
Institutions
- Affiliated Hospital of Hebei University (CN)
- Hebei University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-07-24
- DOI
- https://doi.org/10.3389/fmicb.2025.1586678
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71