Clinical efficacy of modified suanzaoren decoction compared to esazolam tablets in the treatment of chronic insomnia disorder
After the treatment of CID with the modified SZRD and esazolam, they have the comparable clinical efficacy. However, estazolam showed a more consistent treatment effect in subjective sleep quality assessment among the study population, whereas modified SZRD showed a more consistent treatment effect in objective slow-wave sleep maintenance, specifically in N3 stage duration. The registration number was NCT06452953.
Authors
- Wuhong Lin
- Dongsheng Lv (ORCID: https://orcid.org/0000-0002-1559-3588)
- Zhiguo Guo
- Jie Li (ORCID: https://orcid.org/0000-0001-9137-6430)
- Min Chen (ORCID: https://orcid.org/0000-0001-7142-5485)
- Min Liu (ORCID: https://orcid.org/0000-0002-2665-0584)
- Ping Yao (ORCID: https://orcid.org/0000-0002-3831-2005)
- Xiao Guo (ORCID: https://orcid.org/0000-0003-2718-1238)
- Long-Biao Cui
Institutions
- Inner Mongolia People's Hospital (CN)
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
- Xijing Hospital (CN)
- Fourth Hospital of Inner Mongolia (CN)
- Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-07-24
- DOI
- https://doi.org/10.3389/fpsyt.2025.1533652
- Citations
- 3
- Primary Topic
- Sleep and related disorders
- Type
- article
- Field-Weighted Citation Impact
- 6.35
Funders
- Key Research and Development Projects of Shaanxi Province