Prognostic value of blood inflammatory composite markers in the survival of pediatric patients with secondary hemophagocytic lymphohistiocytosis

This study provides preliminary evidence that accessible inflammatory markers like LAR and RPR may assist in early prognostic assessment of pediatric sHLH. These findings highlight the potential utility of routine blood parameters, warranting further validation in larger, stratified cohorts.

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Publication Details

Journal
Frontiers in Pediatrics
Published
2025-07-24
DOI
https://doi.org/10.3389/fped.2025.1458490
Primary Topic
Autoimmune and Inflammatory Disorders Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Prognostic value of blood inflammatory composite markers in the survival of pediatric patients with secondary hemophagocytic lymphohistiocytosis

Zuochen Du, Xin Xie, Nandu Luo, Pei Huang et al.
Frontiers in Pediatrics
Autoimmune and Inflammatory Disorders Research
article

Prognostic value of blood inflammatory composite markers in the survival of pediatric patients with secondary hemophagocytic lymphohistiocytosis

Zuochen Du, Xin Xie, Nandu Luo, Pei Huang, Yan Chen
article en

Abstract

This study provides preliminary evidence that accessible inflammatory markers like LAR and RPR may assist in early prognostic assessment of pediatric sHLH. These findings highlight the potential utility of routine blood parameters, warranting further validation in larger, stratified cohorts.

Frontiers in PediatricsVol. 13
Zunyi Medical University (CN), First People’s Hospital of Zunyi (CN)
Good health and well-being
Openalex Percentile: Top 77%
Autoimmune and Inflammatory Disorders Research
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