Evaluating the Longitudinal Association of Rheumatoid Arthritis Disease Activity With Phenotypic Frailty: Evidence for Secondary Frailty?
Disease activity is independently associated with phenotypic frailty. Increased disease activity over time is associated with worsening frailty status. Future studies are needed to explore this longitudinal relationship and to determine if controlling disease activity can mitigate frailty.
Authors
- Katherine D. Wysham (ORCID: https://orcid.org/0000-0001-8707-7649)
- Dolores Shoback (ORCID: https://orcid.org/0000-0003-2936-4468)
- Courtney Loecker (ORCID: https://orcid.org/0000-0002-2754-5233)
- James S. Andrews (ORCID: https://orcid.org/0000-0003-2302-4358)
- Joshua F. Baker (ORCID: https://orcid.org/0000-0003-0799-7563)
- Elizabeth Wahl (ORCID: https://orcid.org/0009-0004-4249-9492)
- Patricia Katz (ORCID: https://orcid.org/0000-0002-8146-2519)
- Ariela R. Orkaby (ORCID: https://orcid.org/0000-0002-4297-6306)
- Roman Bass
- George R. Mount
- José M. García
- Hannah F. Brubeck (ORCID: https://orcid.org/0009-0007-1964-5318)
- Kylie E. Riggles
Institutions
- Brigham and Women's Hospital (US)
- San Francisco VA Medical Center (US)
- Harvard University (US)
- University of Puget Sound (US)
- University of California, San Francisco (US)
- University of Washington (US)
- VA Boston Healthcare System (US)
- University of Alabama at Birmingham (US)
- VA Puget Sound Health Care System (US)
- Omaha VA Medical Center (US)
- Geriatric Research Education and Clinical Center (US)
- University of California San Francisco Medical Center (US)
- Birmingham VA Medical Center (US)
- Philadelphia VA Medical Center (US)
- University of Nebraska Medical Center (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Arthritis Care & Research
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1002/acr.25615
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 0.00