COVID-19 vaccines-related dermatological manifestations

In the era of Coronavirus Disease 2019 (COVID-19) vaccination drive, there have been various new vaccines getting approval over a period of time. There have been reports of dermatological adverse events with the vaccination. It is imperative to recognize the dermatological adverse effects of each vaccine. In this review, we describe each vaccine-associated dermatological manifestation. A comprehensive narrative review of the literature was performed by searching articles published in PubMed and Google Scholar databases and the following keywords were used: COVID-19 vaccine adverse events, dermatological COVID-19 vaccine events, cutaneous adverse reaction COVID-19 vaccine, and dermatological manifestation COVID-19 vaccine. During the literature search, original articles, review articles, case series, case reports, and other relevant articles published in English language through November 2024 were included for review. A plenty of cutaneous adverse events have been reported from the different phases of vaccine trials. Various dermatological societies and COVID-19 registries have been accumulating such cases since last year. Cutaneous adverse events range from local injection reaction, delayed inflammatory reaction, morbilliform, papulovesicular, and purpuric rash to anaphylaxis. Mass vaccination world over is underway and as per recent data, 13.53 billion COVID-19 vaccine doses have been administered worldwide, with 70.6% of the global population receiving at least one dose to create herd immunity to end this pandemic. It is imperative on the part of care providers to be aware and recognize the dermatological adverse events among the COVID-19 vaccines to educate individuals and render the right counseling.