Steroid-sensitive nephrotic syndrome in children: Korean Society of Pediatric Nephrology clinical practice recommendations

Pediatric nephrotic syndrome is a clinical condition characterized by severe proteinuria, hypoalbuminemia, hyperlipidemia, and generalized edema, most commonly affecting children aged 2 and 6 years. Although standard oral steroid therapy is effective in managing most cases, relapses are common during childhood. Nephrotic syndrome presents significant challenges due to frequent relapses and the potential side effects of long-term drug therapy. In Korea, the absence of a unified national clinical guideline has led physicians to manage pediatric nephrotic syndrome based on diverse clinical guidelines and individual clinical judgment. To address this, the Korean Society of Pediatric Nephrology has developed an evidence-based guideline specifically tailored to the Korean healthcare system. This guideline provides recommendations for the diagnosis and management of steroid-sensitive nephrotic syndrome in children under the age of 18 years.

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Publication Details

Journal
Childhood Kidney Diseases
Published
2025-07-24
DOI
https://doi.org/10.3339/ckd.25.019
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
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article

Steroid-sensitive nephrotic syndrome in children: Korean Society of Pediatric Nephrology clinical practice recommendations

Dong Ah Park, Joo Hoon Lee, Hee Gyung Kang, Eujin Park et al.
Childhood Kidney Diseases
Renal Diseases and Glomerulopathies
article

Steroid-sensitive nephrotic syndrome in children: Korean Society of Pediatric Nephrology clinical practice recommendations

Dong Ah Park, Joo Hoon Lee, Hee Gyung Kang, Eujin Park, Heeyeon Cho, Myung Hyun Cho, Jin‐Soon Suh, Min Hyun Cho, Jeong Yeon Kim, Yeon Hee Lee, Hyun Kyung Lee
article en

Abstract

Pediatric nephrotic syndrome is a clinical condition characterized by severe proteinuria, hypoalbuminemia, hyperlipidemia, and generalized edema, most commonly affecting children aged 2 and 6 years. Although standard oral steroid therapy is effective in managing most cases, relapses are common during childhood. Nephrotic syndrome presents significant challenges due to frequent relapses and the potential side effects of long-term drug therapy. In Korea, the absence of a unified national clinical guideline has led physicians to manage pediatric nephrotic syndrome based on diverse clinical guidelines and individual clinical judgment. To address this, the Korean Society of Pediatric Nephrology has developed an evidence-based guideline specifically tailored to the Korean healthcare system. This guideline provides recommendations for the diagnosis and management of steroid-sensitive nephrotic syndrome in children under the age of 18 years.

Childhood Kidney DiseasesVol. 29(3)
Ulsan College (KR), Korea University Medical Center (KR), Kyungpook National University Hospital (KR), Asan Medical Center (KR), Samsung Medical Center (KR), University of Ulsan (KR), Seoul National University Children's Hospital (KR), The Catholic University of Korea Bucheon St. Mary's Hospital (KR), National Evidenc- based healthcare Collaborating Agency (KR), Chung-Ang University Hospital (KR), Hallym University Sacred Heart Hospital (KR), The Catholic University of Korea Seoul St. Mary's Hospital (KR), Sungkyunkwan University (KR), Catholic University of Korea (KR)
Openalex Percentile: Top 80%
Renal Diseases and Glomerulopathies
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