Extracellular vesicles as prospective biological indicators for midgestational placental complications in the mouse
These findings suggest that placental EVs can reflect compromised placental function and could serve as pathological indicators for the early detection of pregnancy complications. Their potential diagnostic utility could improve maternal and neonatal health outcomes by enabling earlier intervention and monitoring of high-risk pregnancies.
Authors
- Shiva Shafiei
- Laura Montermini
- Nadim Tawil (ORCID: https://orcid.org/0000-0003-2396-6679)
- Janusz Rak (ORCID: https://orcid.org/0000-0002-2912-5566)
- Elaine Lee (ORCID: https://orcid.org/0000-0002-0627-5297)
- Daniel Dufort (ORCID: https://orcid.org/0000-0002-6477-596X)
- M.K. Rana
- Parinaz Kazemi
- Sarah Yull
Institutions
- McGill University Health Centre (CA)
- McGill University (CA)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-07-24
- DOI
- https://doi.org/10.3389/fcell.2025.1636335
- Citations
- 2
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 4.11
Funders
- Fondation de l'Hôpital de Montréal pour enfants
- Canadian Institutes of Health Research