<i>MYH11</i> Suppresses Colorectal Cancer Progression by Inhibiting Epithelial-Mesenchymal Transition via <i>ZEB1</i> Regulation
Our study shows MYH11 curbs CRC growth by blocking EMT and invasion, but ZEB1 overexpression reduces this effect. It uncovers key CRC pathways and suggests MYH11's therapeutic potential.
Authors
- Yingxia Wu
- Yuhang Jiang (ORCID: https://orcid.org/0000-0001-5048-7601)
- Shuang He
- Qi Zhu (ORCID: https://orcid.org/0000-0002-7047-5760)
- Zhe Wang (ORCID: https://orcid.org/0009-0001-7092-671X)
- Shiyong Yu
- Yi-Jun Xu
- Honggang Xiang
Institutions
- Pudong New Area People's Hospital (CN)
Publication Details
- Journal
- Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
- Published
- 2025-01-01
- DOI
- https://doi.org/10.32604/or.2025.063501
- Citations
- 1
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 2.01