Evaluation of the fertilizing and embryo-protecting effects of an improved traditional medicine (Namikawo®) used against female infertility in Brazzaville

Infertility is a public health problem that negatively affects women's social relationships and psychological health.The aim of the present study was to evaluate the fertilizing activity and embryo-protective effect of an improved traditional medicine (Namikawo).The fertilizing and embryo-protective effects of Namikawo were evaluated according to the method reported by Zougrou et al, (2019).To this end, 2 batches of 6 virgin ratlets were treated with respective doses of 1.78 and 5.34 mL/kg of the extract versus 1 control batch (receiving distilled water, at 5 mL/kg) per os for 30 days.On day 21 of treatment, rats were mated with fertile rats.Pregnant rats were set aside and sacrificed on day 15 of gestation for necropsy.Results showed that Namikawo at a dose of 5.34 mL/kg slowed gestation time in 100% of pregnant rats the day after mating, compared with 0% of rats given distilled water.Fertility rates were 300% and 860% for the 1.78 and 5.34 mL/kg doses respectively, compared with 320%

Publication Details

Journal
Journal of Chemical Biological and Physical Sciences
Published
2025-07-24
DOI
https://doi.org/10.24214/jcbps.b.15.3.40108
Primary Topic
African Botany and Ecology Studies
Type
article
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article

Evaluation of the fertilizing and embryo-protecting effects of an improved traditional medicine (Namikawo®) used against female infertility in Brazzaville

Journal of Chemical Biological and Physical Sciences
African Botany and Ecology Studies
article

Evaluation of the fertilizing and embryo-protecting effects of an improved traditional medicine (Namikawo®) used against female infertility in Brazzaville

article en

Abstract

Infertility is a public health problem that negatively affects women's social relationships and psychological health.The aim of the present study was to evaluate the fertilizing activity and embryo-protective effect of an improved traditional medicine (Namikawo).The fertilizing and embryo-protective effects of Namikawo were evaluated according to the method reported by Zougrou et al, (2019).To this end, 2 batches of 6 virgin ratlets were treated with respective doses of 1.78 and 5.34 mL/kg of the extract versus 1 control batch (receiving distilled water, at 5 mL/kg) per os for 30 days.On day 21 of treatment, rats were mated with fertile rats.Pregnant rats were set aside and sacrificed on day 15 of gestation for necropsy.Results showed that Namikawo at a dose of 5.34 mL/kg slowed gestation time in 100% of pregnant rats the day after mating, compared with 0% of rats given distilled water.Fertility rates were 300% and 860% for the 1.78 and 5.34 mL/kg doses respectively, compared with 320%

Journal of Chemical Biological and Physical SciencesVol. 15(3)
Gender equality
Openalex Percentile: Top 77%
African Botany and Ecology Studies
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Evaluation of the fertilizing and embryo-protecting effects of an improved traditional medicine (Namikawo®) used against female infertility in Brazzaville · Journal of Chemical Biological and Physical Sciences (2025) | TGRS Research Map | TGRS