Psychedelics, Spirituality, and Fundamentalism: A Brain Network Approach to Cognitive Flexibility and Rigidity
This viewpoint reconceptualizes mysticism and fundamentalism as brain network disorders, with psychedelics like psilocybin, lysergic acid diethylamide, and N,N-dimethyltryptamine offering potential to modulate these states. By disrupting rigid neural patterns, psychedelics may foster cognitive flexibility, challenge inflexible belief systems, and offer therapeutic value for extremism and mental health disorders.
Authors
- Hongshuang Wang (ORCID: https://orcid.org/0009-0001-8797-4822)
- Xiaohui Wang (ORCID: https://orcid.org/0000-0002-3415-5612)
- A. T. Yang
- Xiangqian Lv
Institutions
- University of Science and Technology of China (CN)
- Chinese Academy of Sciences (CN)
- Uniwersytet SWPS (PL)
- Changchun Institute of Applied Chemistry (CN)
- Institute of Social and Humanities (RU)
- Zhejiang University (CN)
Publication Details
- Journal
- ACS Chemical Neuroscience
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1021/acschemneuro.5c00509
- Primary Topic
- Psychedelics and Drug Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Chinese Academy of Sciences