Performance of fluorescence <i>in situ</i> hybridization in detecting lower <i>versus</i> upper tract urothelial carcinoma

FISH demonstrated overall similar sensitivity and specificity in detecting BC vs. UTUC, while the sensitivity was higher in BC for T1 or ≥T2 tumors. FISH was more sensitive in detecting more invasive or advanced tumors. The tumor stage and the patient's age were predictors of the FISH result in BC.

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Publication Details

Journal
Canadian Journal of Urology
Published
2025-01-01
DOI
https://doi.org/10.32604/cju.2025.063069
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
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article

Performance of fluorescence in situ hybridization in detecting lower versus upper tract urothelial carcinoma

Zhonghua Yang, Song Xu, Hang Zheng, Mengxin Lü
Canadian Journal of Urology
Bladder and Urothelial Cancer Treatments
article

Performance of fluorescence in situ hybridization in detecting lower versus upper tract urothelial carcinoma

Zhonghua Yang, Song Xu, Hang Zheng, Mengxin Lü
article en

Abstract

FISH demonstrated overall similar sensitivity and specificity in detecting BC vs. UTUC, while the sensitivity was higher in BC for T1 or ≥T2 tumors. FISH was more sensitive in detecting more invasive or advanced tumors. The tumor stage and the patient's age were predictors of the FISH result in BC.

Canadian Journal of UrologyVol. 32(6)
Wuhan University (CN), Zhongnan Hospital of Wuhan University (CN), Wuhan Sports University (CN)
Good health and well-being
Openalex Percentile: Top 69%
Bladder and Urothelial Cancer Treatments
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