Bambusa arundinacea (Retz.) Willd. (Tabasheer): Effects on behaviour, Memory, and immunity stressed rat model.
The present study investigated the psychoimmunomodulatory effects of Tabasheer (Bambusa arundinacea (Retz.)Willd.) on stress-induced behavioral, memory, and immune changes in rats.Sprague-dawleyrats were divided into five groups: normal control, stress control, and three groups receiving 200, 400, or 600 mg/kg B. arundinacea orally for 21 days.Stress was induced by forced swimming in cold water.Behavioral and memory parameters were evaluated using spontaneous alternation behavior and passive avoidance tests.Biochemical markers, including brain acetylcholinesterase activity and blood glucose levels, were measured.Immune function was evaluated by total leukocyte count, footpad reaction test, and agglutination method.The relative weights of the spleen, liver, and kidney were also determined.The results showed that stress significantly altered spontaneous alternation behavior, memory retention, and immune function, while increasing brain acetylcholinesterase activity and blood glucose levels compared to normal controls.Tabasheer treatment at 600 mg/kg significantly improved behavioral and memory parameters, reduced brain acetylcholinesterase activity, and regulated blood glucose levels in stressed rats.However, Tabasheer did not significantly affect immune parameters or organ weights.In conclusion, Tabasheer demonstrated protective effects against stress-induced behavioral and memory deficits, supporting its traditional use as a memory enhancer.Further clinical and pharmacological studies are warranted to explore its therapeutic potential and isolate active compounds.
Authors
- Badruddeen Badruddeen
Publication Details
- Journal
- Journal of Phytonanotechnology and Pharmaceutical Sciences
- Published
- 2025-06-02
- DOI
- https://doi.org/10.54085/jpps.2025.5.2.1
- Primary Topic
- Bamboo properties and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00