Normal muscle enzyme levels in classic dermatomyositis: implications for clinical trial endpoints
Muscle involvement in dermatomyositis can present without muscle enzyme elevations in 26–48% of patients. These findings are important to acknowledge in order to interpret muscle enzyme testing within the broader clinical context.
Authors
- Laís Lopes Almeida Gomes (ORCID: https://orcid.org/0000-0001-5396-4362)
- Xiwei Yang
- Chun-Pyn Shen
- Victoria P. Werth (ORCID: https://orcid.org/0000-0003-3030-5369)
- Touraj Khosravi‐Hafshejani (ORCID: https://orcid.org/0000-0001-5395-8480)
- Shae Chambers (ORCID: https://orcid.org/0009-0005-1893-157X)
- Hammad Ali (ORCID: https://orcid.org/0000-0003-1328-480X)
- Aretha On
Institutions
- Philadelphia VA Medical Center (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- British Journal of Dermatology
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1093/bjd/ljaf225
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health