The sodium-glutamate antagonist riluzole improves outcome after acute spinal cord injury: results from the RISCIS randomised controlled trial analysed using a global statistical analytic technique
No funding was received for the present work. The original clinical trial (NCT01597518) was funded by the AO Foundation, United States Department of Defense (DOD), and the Praxis Spinal Cord Institute.
Authors
- Ralph Stanford (ORCID: https://orcid.org/0000-0002-4547-8927)
- Jonathon Ball (ORCID: https://orcid.org/0000-0003-0594-8063)
- Ahmad Nassr (ORCID: https://orcid.org/0000-0002-7160-734X)
- Albert S. Yee
- Darrel S. Brodke (ORCID: https://orcid.org/0000-0001-8749-3765)
- Diana S‐L Chow (ORCID: https://orcid.org/0000-0001-6284-3538)
- Elizabeth G. Toups
- James D. Guest (ORCID: https://orcid.org/0000-0003-0931-0286)
- Kevin E. Thorpe (ORCID: https://orcid.org/0000-0002-7586-3893)
- Jiaxin Huang
- Karlo M. Pedro (ORCID: https://orcid.org/0000-0001-5857-0135)
- Bizhan Aarabi
- James S. Harrop (ORCID: https://orcid.org/0000-0002-0943-3406)
- Michael George Fehlings (ORCID: https://orcid.org/0000-0002-5722-6364)
- Shekar N. Kurpad (ORCID: https://orcid.org/0000-0003-1548-5453)
- Nathaniel P. Brooks (ORCID: https://orcid.org/0000-0002-6355-1147)
- Mohammed Ali Alvi (ORCID: https://orcid.org/0000-0002-7131-079X)
- Ali Moghaddamjou
- Jefferson R. Wilson (ORCID: https://orcid.org/0000-0001-5965-0305)
- James M. Schuster (ORCID: https://orcid.org/0000-0003-3983-5219)
- Paul M. Arnold (ORCID: https://orcid.org/0000-0002-4622-7695)
- Wilson Z. Ray (ORCID: https://orcid.org/0000-0002-3006-8562)
- Peng Huang (ORCID: https://orcid.org/0009-0005-1485-9443)
- Jason Wilson
- Karl M. Schmitt
- Faiz U. Ahmad
Institutions
- University of Maryland, Baltimore (US)
- St. Michael's Hospital (CA)
- University Health Network (CA)
- University of Wisconsin–Madison (US)
- Johns Hopkins University (US)
- University of Miami (US)
- Thomas Jefferson University (US)
- Emory University (US)
- University of Illinois Urbana-Champaign (US)
- Illinois College (US)
- University of Toronto (CA)
- Medical College of Wisconsin (US)
- Washington University in St. Louis (US)
- University of Utah (US)
- Toronto Western Hospital (CA)
- Toronto Rehabilitation Institute (CA)
- Johns Hopkins Medicine (US)
- Royal North Shore Hospital (AU)
- Prince of Wales Hospital (AU)
- Methodist Hospital (US)
- Mayo Clinic in Arizona (US)
- University of Pennsylvania Health System (US)
- Neurological Surgery (US)
- The University of Texas Health Science Center (US)
- University of Houston (US)
- Louisiana State University Health Sciences Center New Orleans (US)
- Neuroscience Research Australia (AU)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- EBioMedicine
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1016/j.ebiom.2025.105863
- Citations
- 7
- Primary Topic
- Spinal Cord Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 10.30
Funders
- U.S. Department of Defense
- AO Foundation