Chronic Pod-Mod E-Cigarette Aerosol Exposure Induces Aortic Dysfunction in Hypercholesterolemic Mice: Role of Oxidative Stress and Inflammation
Chronic inhalation of aerosol from pod-mod e-cigarettes promotes oxidative stress, inflammation, and fibrosis within aortic tissues, significantly impairing passive and vasoactive aortic functions. This evidence provides new insights into the biological processes that increase the risk of adverse cardiovascular events as a result of pod-mod e-cigarette vaping.
Authors
- Yasmeen M. Farra
- Hannah Kim (ORCID: https://orcid.org/0000-0002-9640-7299)
- Cristobal Rivera (ORCID: https://orcid.org/0000-0001-9648-9880)
- Chiara Bellini (ORCID: https://orcid.org/0000-0003-0823-4613)
- Jessica M. Oakes (ORCID: https://orcid.org/0000-0001-9669-0680)
- John Vlahos (ORCID: https://orcid.org/0000-0002-7243-3273)
- Bhama Ramkhelawon (ORCID: https://orcid.org/0000-0002-9087-0995)
- Sharda G. Sabnis
- Hannah I.B. Wilker
- Victoria A. Williams (ORCID: https://orcid.org/0009-0000-7683-9564)
- Jacqueline Matz (ORCID: https://orcid.org/0000-0003-0026-9731)
- Oliver Trejo
Institutions
- Northeastern University (US)
- NYU Langone Health (US)
Publication Details
- Journal
- Arteriosclerosis Thrombosis and Vascular Biology
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1161/atvbaha.125.320908
- Primary Topic
- Air Quality and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.00