Interobserver variability in the histologic evaluation of serrated epithelial change in inflammatory bowel disease among gastrointestinal pathologists: a comparison of two different definitions

The diagnosis of SEC using DEF1 is significantly more reproducible than using DEF2. Utilizing DEF1 is also less likely to miss potentially important cases of SEC. Therefore, DEF1 could be adopted to separate SEC from other serrated lesions and morphologic mimics in IBD.

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Publication Details

Journal
Histopathology
Published
2025-07-24
DOI
https://doi.org/10.1111/his.15523
Citations
3
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
5.45
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article

Interobserver variability in the histologic evaluation of serrated epithelial change in inflammatory bowel disease among gastrointestinal pathologists: a comparison of two different definitions

Ian Brown, Won‐Tak Choi, Gregory Y. Lauwers, Dorukhan Bahceci et al.
3 citations
Histopathology
Inflammatory Bowel Disease
5.45
article

Interobserver variability in the histologic evaluation of serrated epithelial change in inflammatory bowel disease among gastrointestinal pathologists: a comparison of two different definitions

Ian Brown, Won‐Tak Choi, Gregory Y. Lauwers, Dorukhan Bahceci, Rish K. Pai, Joseph Misdraji, Priyanthi Kumarasinghe, Sanjay Kakar, Dongliang Wang
article en
3 citations

Abstract

The diagnosis of SEC using DEF1 is significantly more reproducible than using DEF2. Utilizing DEF1 is also less likely to miss potentially important cases of SEC. Therefore, DEF1 could be adopted to separate SEC from other serrated lesions and morphologic mimics in IBD.

HistopathologyVol. 87(4)
University of California, San Francisco (US), SUNY Upstate Medical University (US), Moffitt Cancer Center (US), Yale University (US), Envoi Specialist Pathologists (AU), Mayo Clinic in Arizona (US), Pathwest Laboratory Medicine (AU)
Good health and well-being
Openalex Percentile: Top 4%
Inflammatory Bowel Disease
5.45
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Interobserver variability in the histologic evaluation of serrated epithelial change in inflammatory bowel disease among gastrointestinal pathologists: a comparison of two different definitions — Ian Brown, Won‐Tak Choi, et al. · Histopathology (2025) | TGRS Research Map | TGRS