Proteomic profiling reveals dynamic regulation of vesicle trafficking across glioma grades

This study highlights the synaptic vesicle cycle as a progressively remodeled pathway in glioma biology. Our findings suggest that vesicle trafficking is a critical, underrecognized feature of glioma pathogenesis and may represent a novel axis for therapeutic exploration.

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Publication Details

Journal
Journal of Neuro-Oncology
Published
2025-07-24
DOI
https://doi.org/10.1007/s11060-025-05151-5
Primary Topic
Cellular transport and secretion
Type
article
Field-Weighted Citation Impact
0.00

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article

Proteomic profiling reveals dynamic regulation of vesicle trafficking across glioma grades

Joanna Reszeć, Dominik Cysewski, Adrian Godlewski, Tomasz Łysoń et al.
Journal of Neuro-Oncology
Cellular transport and secretion
article

Proteomic profiling reveals dynamic regulation of vesicle trafficking across glioma grades

Joanna Reszeć, Dominik Cysewski, Adrian Godlewski, Tomasz Łysoń, Michał Ciborowski, Tomasz Kowalczyk, Adam Jacek Kretowski, Robert Rutkowski, Tomasz Pienkowski, Mikolaj M. Krupa, Marcin Moniuszko, Zenon Dionizy Mariak, Patrycja Mojsak
article en

Abstract

This study highlights the synaptic vesicle cycle as a progressively remodeled pathway in glioma biology. Our findings suggest that vesicle trafficking is a critical, underrecognized feature of glioma pathogenesis and may represent a novel axis for therapeutic exploration.

Journal of Neuro-OncologyVol. 175(2)
Medical University of Białystok (PL)
National Science Foundation, Ministerstwo Edukacji i Nauki, Uniwersytet Medyczny w Bialymstoku
Openalex Percentile: Top 81%
Cellular transport and secretion
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Proteomic profiling reveals dynamic regulation of vesicle trafficking across glioma grades — Joanna Reszeć, Dominik Cysewski, et al. · Journal of Neuro-Oncology (2025) | TGRS Research Map | TGRS