Differentiation of patient-specific induced pluripotent stem cells derived from type 1 diabetes peripheral blood mononuclear cells into pancreatic β-like cells
T1D-iPSCs derived from T1D-PBMCs can be differentiated into insulin<sup>+</sup> β-like cells, albeit with functional immaturity. These cells represent a potential source of seed cells for β-cell replacement therapy in T1D.
Authors
- Jinyan Chen (ORCID: https://orcid.org/0000-0003-4103-7056)
- Zhentao Yu (ORCID: https://orcid.org/0000-0002-5785-8492)
- Jing-jun Jin
- Wei Lin (ORCID: https://orcid.org/0000-0002-2940-6966)
- Kun Wang (ORCID: https://orcid.org/0000-0003-3414-2552)
- Ronghua Liu (ORCID: https://orcid.org/0000-0002-4197-3971)
- Junyong Han (ORCID: https://orcid.org/0009-0000-4467-7628)
Institutions
- Fujian Medical University (CN)
- Fujian Provincial Hospital (CN)
- Fujian Academy of Medical Sciences (CN)
Publication Details
- Journal
- World Journal of Stem Cells
- Published
- 2025-07-24
- DOI
- https://doi.org/10.4252/wjsc.v17.i7.104607
- Citations
- 1
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 2.01