How to Treat Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

Opening by briefly outlining the immunopathology of AAV, which includes GPA, MPA, and EGPA, Terrier explained that these small-vessel vasculitides are characterised by necrotising inflammation associated with ANCA, directed against either proteinase 3 (PR3) or myeloperoxidase (MPO).The disease is systemic and often involves multiple organs, such as the lungs and kidneys.'Where do new agents, like complement inhibitors, fit into the treatment landscape?'Congress Feature EULAR 2025