Unusual, gigantic cystic echinococcosis in a woman living with HIV

IntroductionCystic echinococcosis, or hydatidosis, is a parasite infection that can occur in humans. It can affect all organs, mostly the liver and the lungs. The number, size and evolution of those cysts is mediated by the immune system. Herein we report an unusual presentation of hydatidosis in an immunocompromised woman who lives with HIV.Case presentationOur patient was a 40-year-old female with a 2-decade history of HIV and echinococcal infection. She was in AIDS stage due to poor medical adherence. She presented a medullar toxicity to Albendazole, a medication she had been taking for years to control the echinococcal cysts, which were stable then. Upon stopping the Albendazole, she presented an enlargement of those cysts. Surgery was mandatory, and revealed five liver cysts, a 12cm-large kidney cyst, and a gigantic 20 cm-large retroperitoneal cyst. They were treated successfully, and the patient has been asymptomatic during the last 4 years since surgery, along with maintained HIV suppression.ConclusionHydatidosis can be negatively affected by immunosuppression such as HIV infection. However, the scarcity of the cases studying this association makes it difficult to fully grasp the possible interactions between those two diseases.

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Publication Details

Journal
International Journal of STD & AIDS
Published
2025-07-24
DOI
https://doi.org/10.1177/09564624251362094
Primary Topic
Parasitic infections in humans and animals
Type
article
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article

Unusual, gigantic cystic echinococcosis in a woman living with HIV

Sami Fendri, Chakib Marrakchi, Salah Boujelben, K. Mnif et al.
International Journal of STD & AIDS
Parasitic infections in humans and animals
article

Unusual, gigantic cystic echinococcosis in a woman living with HIV

Sami Fendri, Chakib Marrakchi, Salah Boujelben, K. Mnif, Tarak Ben Jemaa, Mounir Ben Jemâa, E. Elleuch, Z. Mnif, Boussayma Hammami, Amani Bouabdallah
article en

Abstract

IntroductionCystic echinococcosis, or hydatidosis, is a parasite infection that can occur in humans. It can affect all organs, mostly the liver and the lungs. The number, size and evolution of those cysts is mediated by the immune system. Herein we report an unusual presentation of hydatidosis in an immunocompromised woman who lives with HIV.Case presentationOur patient was a 40-year-old female with a 2-decade history of HIV and echinococcal infection. She was in AIDS stage due to poor medical adherence. She presented a medullar toxicity to Albendazole, a medication she had been taking for years to control the echinococcal cysts, which were stable then. Upon stopping the Albendazole, she presented an enlargement of those cysts. Surgery was mandatory, and revealed five liver cysts, a 12cm-large kidney cyst, and a gigantic 20 cm-large retroperitoneal cyst. They were treated successfully, and the patient has been asymptomatic during the last 4 years since surgery, along with maintained HIV suppression.ConclusionHydatidosis can be negatively affected by immunosuppression such as HIV infection. However, the scarcity of the cases studying this association makes it difficult to fully grasp the possible interactions between those two diseases.

International Journal of STD & AIDSVol. 36(13)
Hopital Universitaire Hedi Chaker (TN), Hopital Universitaire Habib Bourguiba (TN)
Good health and well-being
Openalex Percentile: Top 73%
Parasitic infections in humans and animals
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Unusual, gigantic cystic echinococcosis in a woman living with HIV — Sami Fendri, Chakib Marrakchi, et al. · International Journal of STD & AIDS (2025) | TGRS Research Map | TGRS