Simultaneous expression of epithelial and immune cell markers in circulating tumor cells identified in patients with stage 4 breast cancer
Collectively, these genomic and proteomic features distinguish im.CTCs from previously reported circulating cells may represent a novel form of tumor cell plasticity.
Authors
- Peter Kühn (ORCID: https://orcid.org/0000-0003-2629-4505)
- Rafael Nevarez
- Valerie Hennes
- Craig D. Shriver (ORCID: https://orcid.org/0000-0001-8993-5811)
- James Hicks (ORCID: https://orcid.org/0000-0001-5353-4338)
- Lorraine Tafra
- Andrés Rivera (ORCID: https://orcid.org/0000-0002-3223-8182)
- Nikki Higa (ORCID: https://orcid.org/0000-0003-3236-8929)
- Anand Kolatkar (ORCID: https://orcid.org/0000-0002-8621-1073)
- Carol Tweed
- Adam I. Riker
- Jeremy G. Perkins
- Young Lee (ORCID: https://orcid.org/0000-0001-9205-1785)
- Audrey Limb
Institutions
- University of Southern California (US)
- Uniformed Services University of the Health Sciences (US)
- Anne Arundel Medical Center (US)
- Walter Reed National Military Medical Center (US)
- Maryland Oncology Hematology (US)
- Maryland Department of Natural Resources (US)
- USC Norris Comprehensive Cancer Center (US)
- Convergent Science (United States) (US)
- Dermatology Specialists (US)
Publication Details
- Journal
- Communications Medicine
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1038/s43856-025-01024-0
- Citations
- 3
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 3.14
Funders
- U.S. Department of Defense
- Breast Cancer Research Foundation
- Henry M. Jackson Foundation
- National Institutes of Health
- Uniformed Services University of the Health Sciences
- National Cancer Institute