Niosomes as versatile nanocarriers in diabetes research

Abstract Metabolic disorder is characterized by elevated blood glucose levels that eventually leads to diabetes mellitus. The rising prevalence of diabetes mellitus has created a significant healthcare burden worldwide. Current treatments encounter restrictions in proper management of this condition due to their severe side effects. Therefore, there is a growing interest in investigating the potentials of natural products as an alternative measure in the prevention and treatment of diabetes mellitus. Natural products are advantageous for their minimal side effects, biocompatibility and cost-effectiveness; however, they are highly prone to degradation, which implies the need for modification strategies for proper utilization of these sources. The nanotechnology field has seen the emerging benefits of niosomes for drug delivery applications pertaining to their unique versatility. This article aims to discuss the versatility and benefits of niosome systems focusing on diabetes mellitus applications.