Association between neonatal brain volume and school-age executive function in children born moderate-to-late preterm
This study described the associations between neonatal brain volumes and executive function (EF) outcomes at 9 years in children born moderate-to-late preterm (MLP), a group that has been under researched compared with children born very preterm. There was limited evidence of an association between neonatal brain volumes and school-age EF outcomes in children born MLP, contrasting previous findings in very preterm children. This suggests that neonatal brain volumes alone do not effectively predict school-age EF in children born MLP, highlighting the need for more sensitive neuroimaging techniques and identification of other important predictors of long-term outcomes in this population.
Authors
- Rheanna Mainzer (ORCID: https://orcid.org/0000-0002-5933-8917)
- Jeanie L.Y. Cheong (ORCID: https://orcid.org/0000-0001-5901-0455)
- Leona Pascoe (ORCID: https://orcid.org/0000-0001-5859-943X)
- Rachel Ellis (ORCID: https://orcid.org/0000-0003-2355-5407)
- Luciano Rossetti (ORCID: https://orcid.org/0000-0003-3999-9897)
- Deanne K. Thompson (ORCID: https://orcid.org/0000-0001-8017-5756)
- Peter J. Anderson (ORCID: https://orcid.org/0000-0001-7430-868X)
- Lex W. Doyle (ORCID: https://orcid.org/0000-0002-7667-7312)
- Joy E. Olsen (ORCID: https://orcid.org/0000-0002-8006-0139)
Institutions
- Children's Hospital of Orange County (US)
- Royal Women's Hospital (AU)
- Mental Health Research Institute (AU)
- The University of Melbourne (AU)
- University of California, Irvine (US)
- Murdoch Children's Research Institute (AU)
- Monash University (AU)
Publication Details
- Journal
- Pediatric Research
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1038/s41390-025-04274-9
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Australian Government
- Medical Research Council
- National Health and Medical Research Council