EFFECTS OF ROPIVACAINE ADMINISTRATION UNDER DIFFERENT OXYGEN CONCENTRATIONS ON PATIENTS UNDERGOING CESAREAN SECTION: A META-ANALYSIS

This meta-analysis evaluated the effects of ropivacaine under varying oxygen concentrations during caesarean section surgeries.A systematic review identified 12 relevant studies, categorizing participants into low-dose (LD) and high-dose (HD) ropivacaine groups.Data were analysed using RevMan 5.3 with fixed-or random-effects models.No significant differences were observed between HD and LD groups regarding surgical duration or anaesthesia duration.However, HD ropivacaine was associated with significantly higher neonatal Apgar scores.A high degree of heterogeneity was observed for sensory block duration, with the LD group showing notably shorter block duration.The findings indicate that oxygen concentration markedly affects ropivacaine's clinical performance in caesarean sections.HD ropivacaine provides enhanced anaesthesia, longer sensory block, better postoperative analgesia, and superior neonatal outcomes, supporting its preferential use in such surgical contexts. RezumatAceast meta-analiz a evaluat efectele ropivacainei administrate n timpul operaiilor de cezarian, n funcie de concentraia de oxigen din mediul operator.Au fost incluse 12 studii relevante, iar participantele au fost mprite n dou grupuri, n funcie de doza de ropivacain administrat: doz mic (LD) i doz mare (HD).Analiza datelor a fost realizat cu ajutorul programului RevMan 5.3.Rezultatele au artat c nu exist diferene semnificative ntre cele dou grupuri n ceea ce privete durata interveniei chirurgicale sau durata anesteziei.A fost observat o variabilitate ridicat ntre studii n ceea ce privete durata blocului senzorial, ns aceasta a fost semnificativ mai scurt n grupul cu doz mic.n concluzie, concentraia de oxigen din mediul operator influeneaz semnificativ eficiena ropivacainei n timpul operaiilor de cezarian.Administrarea unei doze mari de ropivacain se asociaz cu beneficii superioare: anestezie mai eficient, durat mai lung a efectului, control mai bun al durerii postoperatorii i scoruri neonatale mbuntite.