IgG and Fc Receptor Genetic Variation Associates With Functional Antibody Responses in a DNA and Protein Candidate HIV Vaccine Trial
Genetic variation in both antibodies and FcRs associated with levels of HIV-vaccine-elicited functional antibodies. Significant regional differences in distribution of this variation support the need for vaccine testing in diverse populations.
Authors
- Justin Pollara (ORCID: https://orcid.org/0000-0003-1892-4722)
- Nigel Garrett (ORCID: https://orcid.org/0000-0002-4530-234X)
- Haleigh E. Conley (ORCID: https://orcid.org/0000-0002-6370-6532)
- James G. Kublin (ORCID: https://orcid.org/0000-0003-1279-3741)
- Shalini Jha (ORCID: https://orcid.org/0000-0002-9792-2161)
- Daniel E. Geraghty (ORCID: https://orcid.org/0000-0001-7702-5650)
- Guido Ferrari
- Susan Watts
- Georgia D. Tomaras (ORCID: https://orcid.org/0000-0001-8076-1931)
- Cynthia L. Monaco (ORCID: https://orcid.org/0000-0003-3093-5563)
- Song Young Oh (ORCID: https://orcid.org/0009-0005-4827-8014)
- Cliburn Chan
Institutions
- Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa (ZA)
- Duke University (US)
- Centre for the AIDS Programme of Research in South Africa (ZA)
- University of Rochester Medical Center (US)
- Fred Hutch Cancer Center (US)
- University of KwaZulu-Natal (ZA)
Publication Details
- Journal
- JAIDS Journal of Acquired Immune Deficiency Syndromes
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1097/qai.0000000000003734
- Primary Topic
- Monoclonal and Polyclonal Antibodies Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00