Photopharmacology reveals high-specificity linkage of Ca2+ entry at TRPC6 nanodomains to NFAT activation in mast cells
We report here the exceptionally efficient and specific modulation of mast cell activity by TRPC6 photopharmacology.
Authors
- Johannes Pilic (ORCID: https://orcid.org/0000-0001-8452-0879)
- Bernadett Bacsa (ORCID: https://orcid.org/0000-0003-2201-4721)
- Denis Krivić (ORCID: https://orcid.org/0000-0002-2852-4522)
- Roland Malli (ORCID: https://orcid.org/0000-0001-6327-8729)
- Klaus Groschner (ORCID: https://orcid.org/0000-0002-8659-377X)
- Sanja Ćurčić
- Olga Panasiuk
Institutions
- Medical University of Graz (AT)
- BioTechMed-Graz (AT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-07-24
- DOI
- https://doi.org/10.3389/fimmu.2025.1595036
- Citations
- 1
- Primary Topic
- Neurobiology and Insect Physiology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.91
Funders
- Austrian Science Fund