Sensory-selective Peripheral and Neuraxial Nerve Blockade with 2′,6′-Pipecoloxylidide
PPX provides sensory-selective local and neuraxial anesthesia with a good safety profile. The sensory selectivity may be attributable to the particular hydrophilic-hydrophobic balance of PPX.
Authors
- Matthew Torre (ORCID: https://orcid.org/0000-0002-5221-7776)
- Zahra Vahedi (ORCID: https://orcid.org/0000-0003-4682-5502)
- Daniel S. Kohane (ORCID: https://orcid.org/0000-0001-5369-5932)
- Yueqin Zheng (ORCID: https://orcid.org/0009-0004-8912-6044)
- Tianrui Xue (ORCID: https://orcid.org/0000-0002-2485-7514)
- Steven J. Staffa (ORCID: https://orcid.org/0000-0002-7588-7596)
- Longtu Chen (ORCID: https://orcid.org/0000-0001-9018-7734)
- Bin Feng (ORCID: https://orcid.org/0000-0001-9277-211X)
- Shuanglong Chen (ORCID: https://orcid.org/0000-0002-2671-3151)
- Claire A. Ostertag‐Hill (ORCID: https://orcid.org/0000-0002-1407-6896)
- Rachelle Shao (ORCID: https://orcid.org/0000-0002-8772-8269)
Institutions
- Brigham and Women's Hospital (US)
- Boston Children's Hospital (US)
- Harvard University (US)
- University of Connecticut (US)
- China Pharmaceutical University (CN)
Publication Details
- Journal
- Anesthesiology
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1097/aln.0000000000005679
- Citations
- 3
- Primary Topic
- Anesthesia and Pain Management
- Type
- article
- Field-Weighted Citation Impact
- 6.02