Customized Chromosomal Microarrays for Neurodevelopmental Disorders
Customized CMA offers enhanced detection of clinically relevant CNVs and provides a framework for prioritizing novel candidate genes based on biological network integration. This approach improves diagnostic accuracy in NDDs and identifies new targets for future functional and translational studies, highlighting the importance of glial involvement and immune-related pathways in neurodevelopmental pathology.
Authors
- Kristina Gotovac (ORCID: https://orcid.org/0000-0001-5892-7392)
- Thomas Liehr (ORCID: https://orcid.org/0000-0003-1672-3054)
- Fran Borovečki (ORCID: https://orcid.org/0000-0002-5178-7929)
- Martina Rinčić (ORCID: https://orcid.org/0000-0003-0390-5967)
- Lukrecija Brečević
- Ines Doder
Institutions
- University Hospital Centre Zagreb (HR)
- University of Zagreb (HR)
- University of Applied Health Sciences (HR)
- Primary Health Care (QA)
- Jena University Hospital (DE)
- Friedrich Schiller University Jena (DE)
Publication Details
- Journal
- Genes
- Published
- 2025-07-24
- DOI
- https://doi.org/10.3390/genes16080868
- Primary Topic
- Genetics and Neurodevelopmental Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission